AANS/CNS Section on Tumors II

The Section Sessions include oral presentations of top-rated abstracts, announcements of awards, lectures from accomplished speakers and moderated discussions on current topics.

Check back throughout the year as new topics, speakers and presentations are announced for this session.

Wednesday, April 29
2:00 pm - 5:00 pm

Moderator(s): Frank Joseph Attenello III, MD; Gavin Peter Dunn, MD, PhD, FAANS; Marc Louis Otten, MD, FAANS ; Anthony C. Wang, MD

2:00 pm - 2:04 pm

Introduction to the Session

Frank Joseph Attenello III, MD

2:05 pm - 2:20 pm

Lessons Learned: a Review of Failed GBM Trials

Patrick Wen, MD

2:21 pm - 2:36 pm

How will Phase 0 trials Improve our Success?

Nader Sanai, MD, FAANS

2:37 pm - 2:52 pm

Model Limitations - are our Pre-clinical Data Translating?

Terence Burns, MD, PhD

2:53 pm - 3:08 pm

Tumor Genomics and Biology for "Personalized" Trials

Daniel P. Cahill, MD, PhD, FAANS

3:09 pm - 3:24 pm

Case Discussions

Peter Edward Fecci, MD, FAANS

3:25 pm - 3:34 pm

Ex-Vivo Multi-Electrode Analysis Reveals Spatiotemporal Dynamics of Ictal Behavior at the Infiltrative Margin of Gliomas

Brian Gill, MD

3:35 pm - 3:44 pm

Local Combination Therapy of Poly-ADP-Ribose-Polymerase-Inhibitor Olaparib and Temozolomide-Etoposide From a Biodegradable Paste Potentiates Radiotherapy and Prolongs Survival

Riccardo Serra

3:45 pm - 3:54 pm

Resting-state fMRI Detects Alterations in Whole Brain Connectivity Related to Tumor Biology in Glioma Patients

Veit Stoecklein (Germany)

3:55 pm - 4:04 pm

Modeling the Genetic, Transcriptomic, and Cell Surface Antigen Heterogeneity of Glioblastoma Using Patient Derived Tumor Organoids

Daniel Zhang

4:05 pm - 4:14 pm

Exploiting Inherent DNA Damage Repair Defects in IDH1/2 Mutated Gliomas With The CNS-Penetrant PARP Inhibitor BGB290

Christopher S. Hong, MD

4:15 pm - 4:24 pm

Differentiating Recurrent Tumor and Treatment Effect in Post-Treatment Recurrent High-Grade Glioma using a Convolutional Neural Network

Deborah Boyett

4:25 pm - 4:34 pm

Longitudinal Analysis of Serum-derived Extracellular RNA for Monitoring of Treatment Response to Dacomitinib in Adult Patients with EGFR Amplified Recurrent Glioblastoma

Anudeep Yekula, MD

4:35 pm - 4:44 pm

Reprogrammed TCA Cycle Maintains a Stem-Like Epitranscriptome and Therapeutic Persistence in Glioblastoma Stem Cells

Leo Kim

4:45 pm - 4:54 pm

Identification of 48 Novel Long Noncoding RNAs (lncRNAs) Modulating Glioblastoma Invasion via CRISPR-Interference Functional Screen

Frank Joseph Attenello III, MD

4:55 pm - 5:00 pm

Question and Answer Session