1277. Percutaneous Vertebroplasty in the Management of Painful Compression Vertebral Body Fractures.

Authors: Uladzislau Ulasavets; Uladzislau Ulasavets; Rafał Morga; Ewelina Grzywna; Jarosław Polak; Artur Jurczyszyn; Katarzyna Jasińska; Krzysztof Stachura; Marek Moskała; Borys Kwinta (Krakow, Poland)

Introduction: In a 2010 study, the prevalence of vertebral compression fractures (VCF) ranged between 30% and 50% in adults older than 50 years of age. More than 40% of patients will fail to achieve significant pain relief by 12 months. This study was designed to investigate the role of vertebroplasty in the pain management in VCF patients. Methods: Data on management and outcomes for patients with VCF were collected retrospectively. Past medical history and operating protocols were investigated. Primary endpoint was technically successful procedure. Assessment of clinical effectiveness and pain relief was measured by the visual analogue pain scores (VAS), Roland-Morris disability questionnaire, modified Rankin Scale(mRS), and the Oswestry Disability Index. Results: 109 patients with compression vertebral body fractures of thoracic and/or lumbar spine have been enrolled. Multiple myeloma(MM) fractures were more often comparing to osteoporotic fractures (72 vs 37). BMI hadn’t differ significantly between MM patients and osteoporotic patients (26,77±3,52 vs 25,39±6,45). Mean preoperative VAS for MM group was 5,1±3,13 and 5,6 ± 2,61 for osteoporotic patients accordingly. High-viscosity spinal cement was used and all performed procedures were technically successful in both groups. Vertebroplasty has resulted in pain relief with greater effect in multiple myeloma patients (p=.0068). MM patients had statistically higher mRS at discharge comparing to osteoporotic fracture group (1 vs 0, p=.02). Patients with history of trauma spent more days at the hospital (2 vs. 4, p=.03). No major complication occurred. Conclusion: The use of percutaneous vertebroplasty is effective as the pain management method, especially in multiple myeloma patients with vertebral involvement.