1302. Encephalocele Clinical Profile, Management and Outcome in Developing Country-Nepal

Authors: Dr Prakash Kafle; Dr. Babita Khanal; Prof Mohan Sharma, MS; Prof Sushil Shilpakar, MS; Dr. Gopal Sedain; Dr. Amit Pradhananga; Dr. Ram Shrestha; Dr. Binod Bhandari, MS (Waling-Rambaccha, Nepal)

Introduction: There is limited study done on Encephalocele in Nepal. As Institute of Medicine, Tribhuvan University Teaching Hospital (TUTUH) is one of the oldest and largest tertiary care hospitals with multidisciplinary team, most of the cases of encephalocele are received from different parts of the nation. So the present study seems feasible and aims to address the gap in the literature on encephalocele from developing countries like Nepal. This study aims to characterize the clinical profile, management and outcome of Encephalocele at tertiary care center in Nepal. Methods: This is a prospective observational study conducted at Institute of Medicine, Tribhuvan University Teaching Hospital (TUTH) Kathmandu, Nepal from September 2014 to August 2017. Results: Total of 25 cases were surgically managed in the present study. The mean age was 12.27 month (range: 1 day to 84 month).There were 11 male and 14 female with male to female ratio of 1:1.26. Occipital Encephalocele was the most common variant. Lump in the head (n=11) was the commonest clinical presentation followed by hyperteliorism (n=10). One patient presented with cleft lip and one had CSF discharge in case of occipital Encephalocele. Bony defect was the common radiological findings. Excision and repair was most common mode of surgery with good outcome. Mortality and morbidity were 4% and 20% respectively. Conclusion: Surgical excision and repair is standard treatment with relative good outcome when treated early.