1350. An unusual case of left Abducens Nerve Palsy, due to Invasive aspergillus fumigatus, of the left orbit, pterygopalatine fossa and cavernous sinus, presenting in an immunocompetent woman: A case report and review of the literature

Authors: Moleca Ghannam; Basad Essa, MD; Mazen Al-Hakim, MD; Barbara Gordon (Royal Oak, MI)


The presence of Aspergillus in the central nervous system (CNS), is an uncommon infection, mainly and rarely seen among immunocompetent patients. We describe left Abducens Nerve Palsy in a patient with Invasive aspergillosis of the left orbit, pterygopalatine fossa and cavernous sinus. This kind of infection can spread rapidly to the surrounding structures, often fatal and generally affects immunocompromised hosts. We will discuss the imaging and labs studies performed, and the management plan that ended in an improvement in her symptoms and the prevention of further extension to the CNS.