1060. Contrast enhancement of vascular walls of intracranial arteriovenous malformations indicates high inflammatory activity.
Authors: Athanasios Petridis, MD, IFAANS; Jan Cornelius; Hans Jakob Steiger; Rebecca May (Duesseldorf, Germany)
Introduction: Until today it is not clear which brain AVMs should be treated and which should be just observed. Objective criteria beyond growth in serial MRIs or angiographies are lacking. The use of black blood MRI is currently under investigation for evaluating the rupture risk of cerebral aneurysms, however its use for assessment of AVMs is not being evaluated. We conducted a feasibility study on the application of black blood MRI (bbMRI) in AVMs to assess rupture risk. Methods: Retrospective study of N=10 patients with intracranial AVMs and N=4 patients with arteriovenous fistulas who received a black blood MRI before Treatment. Results: In 9 of 10 AVM niduses, vessel wall contrast enhancement was seen irrespective of rupture or size. All arteriovenous fistulas (4 / 4) were contrast enhancing irrespective of rupture. Conclusion: Arteriovenous malformations are in a permanent inflammatory stage. BbMRI is a feasible method of identifying inflammation in AVMs and arteriovenous fistulas although it does not allow conclusions on their rupture risk. However future prospective studies are needed to evaluate whether bbMRI contrast enhancement could correlate with rupture risk.