1012. A SINGLE CENTER PROSPECTIVE STUDY OF GLOW 800 IN NEUROVASCULAR AND BRAIN TUMOR SURGERY
Authors: Matthew Welz; Matthew Welz, MS; Devi Patra; Chandon Krishna, MD; Bernard Bendok (Phoenix, AZ)
Glow800 is a single center prospective study that compares the second-generation visualization tool to standard ICG visualization. This comparison study will assess a new light filter which allows visualization of ICG through the oculus to the currently available method that diverts attention away from the surgical field to a monitor. Using standard of care procedures will allow us to regulate whether this new modality is equal to or better than the current modality. We believe the new visualization tool has the potential to improve spatial interpretation, leading to the better recognition of aneurysm remnants or vessel compromise.
Patients undergoing intracranial tumor resection, aneurysm clipping, and other vascular pathology treatments meet the criteria for the study. The investigators will simultaneously capture intraoperative footage of ICG using the current method and the new method. External blinded reviewers and internal reviewers will monitor the footage and compare, identifying any discrepancies that might occur between the proven and new.
The primary endpoint is to demonstrate that Glow800 is comparable to the standard of care FL800. Secondary endpoints include reduced operation time, improved spatial interpretation, better identification of arteries, and the ability to assess cortical perfusion and immediate intra-operative identification of areas of ischemia.
The Glow800 study will assess whether the new technology is up to standards and as effective as the current commercially available product with the added ability to visualize ICG in the operating field instead of on a monitor