1006. A Literature Review Comparing Occlusion, Recanalization, and Retreatment Rates of Hydrogel Coils and Platinum Coils

Authors: Karl Rony Abi-Aad; Jennifer Ward, MBA; Jason Kniss; Devi Patra, MD; Matthew Welz, MS; Evelyn Turcotte; Ryan Hess; Brian Kalen; Andrew Pines; Bernard Bendok (Phoenix, AZ)

Introduction: The first-generation HydroCoil (MicroVention, Tustin, California, USA), which consists of an expandable hydrogel coated coil, was developed to improve the high rate of aneurysm recurrence following embolization. However, it presented several technical difficulties, including difficulty of coil deployment. A second-generation HydroCoil was developed to correct the technical difficulties associated with the first-generation by making it softer and expand more slowly. We performed a systematic literature review on the first and second-generation hydrogel coils to evaluate their clinical efficiency. Methods: Multiple databases were queried using the terms “ HydroCoil ”, “Hydrogel”, “ Hydrosoft ”, “ Hydrofill ”, or “ Hydroframe ”. Studies with long term outcome were included in our analysis. Reported outcomes were initial occlusion rate, recanalization, and retreatment rates. Results: Overall, 6 studies comparing the first-generation hydrogel coil (1HGC) to bare platinum coils (BPC) were included in the review with a total of 1403 aneurysms. Seven studies comparing the second-generation hydrogel coil (2HGC) and the BPC were included with a total of 1909 aneurysms. The 1HGC did not show a significant di